Biochemistry Web Links

General Biochemistry
Structure Databases
Sequence Databases
Molecular Visualization
Online Journals
Government Resources
Laboratory Protocols
Boyer Text Chapter Links
Cutting Edge Links
  AIDS Therapies
  Alcohol Abuse
  Anthrax
  Aspirin
  Botox
  Catalytic Antibodies
  DNA Fingerprinting
  Endocrine Disruptors
  Fat Blockers
  Homocysteine
  Hot Careers
  Lactose Intolerance
    Low-Carb Diets
  Methanol as Fuel
  Minimal Genomes
  Molecular Recognition
  Nitric Oxide and Viagra
  Prions
  Resveratrol
  Ribozymes
  Shotgun Sequencing
  Telomeres
  Thermo-Depolymerization
  Visionaries of Science


General

The NCBI Home Page: Sequence and structure databases, more...
PubMed: Journal search engine
Biochemist Online
Lab Velocity: Products, tools, protocols, news, etc...
MIT Biology Hypertextbook: Smorgasboard of biology and biochemistry

Structure Databases

RCSB: The home site for all PDB files
The NCBI Structure Section

Gene and Protein Sequences

NCBI BLAST: Protein and nucleic acid sequence database and comparison

Molecular Visualization

Jmol Molecular Viewer Project Home Page
MolviZ.org: Molecular Visualization tutorials and resources
Protein Explorer: Molecular visualization freeware.
Chime plug-in from MDLI (not compatible with all browsers and operating systems).
FoldIt: A freeware molecular modeling program for the Mac.
Cn3D: A helper application to view 3D structures from the Entrez retrieval service.
DeepView/Swiss PDB viewer: Molecular visualization freeware

Online Journals

Scientific American
The Journal of Biological Chemistry
Nature Magazine
Science Online: The weekly journal of the American Association for the Advancement of Science

Government Resources

The U.S. Food and Drug Administration

Laboratory Protocols

Protocols Online
Molecular Biology Protocols

Boyer Text Chapter Links

Chapter 1

General, Organic and Biochemistry
Cells and Cell Structure
The Tree of Life

Recombinant DNA Debate
A Visit With Dr. Francis Crick
Medical Researcher-Immunologist - Dr. James Watson
DNA Interactive
DNA from the Beginning
Signalling pathways

Chapter 2

Water Ionization
Chemical Properties of Water
pH Regulation During Exercise
Nutrients and Solubility
Dialysis in the Kidneys

Chapter 3

Amino Acids: images and properties
Amino Acid Information
Amino Acid Quiz
A Virtual Protein Purification Lab
Protein Sequencing
Proteomics and Bioinformatics
Amino Acid ID Quiz (requires Chime)
Iron Use and Storage in the Body

Chapter 4

An Online Course on Protein Structure
Studying Protein Structures with Chime-Some Examples
Alpha Helices and Beta Pleated Sheets (requires Chime)
An Exploration of Hemoglobin (requires Chime)
Protein Structure Classifications (requires Chime)
Protein Structure Quiz
Hemoglobin and the Heme Group

Chapter 5

Energy, Enzymes, and Catalysis Problem Set
Kinetics and Enzyme Inhibition
Exploring the Enzyme Lysozyme (requires Chime)

Chapter 6

Enzyme Cofactors
Coenzymes

Chapter 7

Carbohydrates in 3D (requires Chime)
Glycoproteins

Chapter 8

Lipid Structures in 3D (some pages require Chime.)
Major Roles of Biological Lipids

Chapter 9

Bilayer Membranes (requires Chime)
Lipid Bilayers in 3D (requires Chime)
Phospholipids in Cell Membranes
Protein Ion Channel
Membrane transport (one image requires Chime.)
Membrane Mimic Test for E. Coli

Chapter 10

Nucleotides in 3D
Survey of Nucleotides
Left Handed DNA
DNA & RNA Structure (requires Chime)
Hoof and Mouth Disease Virus
Journey into DNA

Chapter 11

National Human Genome Research Institute (NHGRI)
Saccharomyces Genome Database
Genome Research at the Broad Institute/Whitehead/MIT
Anti-Cancer Mushrooms
Genetics Education Center
Cracking the Code of Life
Sequence for Yourself
DNA Repair

Chapter 12

tRNA Tour (requires Chime)
Ribosome Structure

Chapter 13

Recombinant DNA Debate
Recombinant DNA Technology Problem Set
A Graphics Gallery of Biotechnology
Recombinant DNA and Gene Transfer Regulations
Drugs from Tobacco
Transgenic Plants

Chapter 14

Metabolic Pathways of Biochemistry
Center for Inherited Disorders of Energy Metabolism (CIDEM)
Inborn Errors in Metabolism

Chapter 15

Introduction to Glycolysis
Do It Yourself Glycolysis
Step by Step Glycolysis
Glycolysis Pathway
Structure of Glycolysis Intermediates (requires Chime)
Glycolysis (some pages require Chime)
Glycogen Biosynthesis & Galactose Pathway (some pages require Chime)

Chapter 16

The Citric Acid Cycle Graphically
The Citric Acid Cycle (some pages require Chime)
Phosphogluconate Pathway (some pages require Chime)
Step by Step Krebs cycle
Oxidative Decarboxylation of Pyruvate
G6PD Deficiency

Chapter 17

Vision and Light-Induced Molecular Changes
Energy for the Body - Oxidative Phosphorylation
Oxidative Phosphorylation
Citric Acid Cycle Intermediates (requires Chime)
Biological Oxidations
Oxidations and Electron Transport
Bioenergetics and Oxidative Phosphorylation
Photosynthetic electron transport
Photosynthesis - The Dark Reactions
Photosynthetic Molecules in 3D

Chapter 18

Activation & Transport of Fatty Acids (some pages require Chime)
Beta-Oxidation of Fatty Acids (even chain)
Cholesterol Biosynthesis
Fatty Acids Tutorial
Lipid Metabolism

Chapter 19

Urea Cycle (some pages require Chime)
Amino Acid Metabolism
Nucleotide Metabolism
Nucleotide Metabolism in Muscle

Chapter 20

Animations for Concepts in Biochemistry
A Virtual Classrooom for Concepts in Biochemistry

Special Topics I: Signal Transduction

Signalling pathways

Special Topics I: Molecular Immunology

The Molecular Immunology Foundation

Cutting Edge Links

AIDS Therapies

National Institute of Allergy and Infectious Diseases (NIAID) – Guide for development of AIDS therapies
US Food and Drug Administration (USDA) – Approved drugs for HIV/AIDS
Joint United Nations Programme on HIV/AIDS (UNAIDS) – World AIDS epidemic statistics and solutions

Alcohol Abuse

The Higher Education Center for Alcohol and Other Drug Prevention
Annals of Internal Medicine – studies on Asian American ALDH alleles
Other links to alcohol related sites
Metabolism of alcohol
Naltrexone – the anti-pleasure medicine
Disulfuram – mechanism of toxicity

Anthrax

Centers for Disease Control (CDC) – Anthrax symptoms, treatment, and use as a weapon of biological warfare
Nature Magazine –Information on anthrax toxin research
University of Wisconsin – Microbiology of Bacillius anthracis

Aspirin

'An Aspirin a Day...' Just Another Cliché?
Aspirin for Reducing Your Risk of Heart Attack and Stroke: KNOW THE FACTS
TheAspirin Foundation of America
Bayer AG Aspirin Page

Botox

Botox.com –- Official site from Allergan, producers of cosmetic Botox
FDA Approves Botox to Treat Frown Lines – the FDA press release
How Botox Works – A tutorial from howstuffworks.com

Catalytic Antibodies

Catalytic Antibodies
Abzymes: Catalytic Antibodies (some images require Chime)
More Abzymes

DNA Fingerprinting

Frontline – the Case of Ronald Cotton
Great index of DNA/forensic sites
Reliagene – Private DNA identification laboratory
Paternity Testing
DNA analysis units – The FBI

Endocrine-Disrupting Compounds

The Why Files – endocrine disrupter pages
Tulane University –- Estrogens and estrogen-mimicking compounds
Environmental Protection Agency – endocrine disruptor’s research initiative
Endocrine/Estrogen Letter – links
U.S. Geological Survey –- endocrine disruptor page

Fat Blockers

Proctor and Gamble – Olean information
Frito-Lay – the maker of WOW chips (now relabeled as "Light")
FDA NEWS – Olestra and other fat substitutes
The Diabetes Monitor – information about Olestra
Center for Science inthe Public Interest (CSPI) – the facts about Olestra
The Olestra Project – Harvard University
Bluffton University – the structure of Olestra (requires Chime)
Xenical (Orlostat) – home page
FDA Approves Orlistat – Announcement

Homocysteine

American Heart Association – Homocysteine, folic acid, and cardiovascular disease

Hot Careers

Jobscience.com – biochemistry jobs
Science Careers

Lactose Intolerance

National Institutes of Health – Lactose intolerance overview
Lactose.net – Listing of many sites
Planet Lactose – Good compilation of resources for lactose intolerance

Low-Carb Diets

The Atkins Center
AtkinsDietAlert.org – A resource for people with questions and concerns about high-protein diets

Methanol as Fuel

American Methanol Institute
Alternative Fuels Data Center
The Official Site of the National Biodiesel Board
Alternative Fuels Data Center
Biomass Resources for Energy and Industry
Biomass
UM-BBD Graphics Index
C1 Metabolic Cycle Pathway Map
Renewable Energy Economic and Environmental Issues
Biofuels USDA-ARS
EPA’s Fact Sheet on Methanol

Minimal Genomes

J.Carig Venter Institute
Institute for Genomic Research (TIGR)
Dr. Eckard Wimmer – head of the team that synthesize an artificial polio virus

Molecular Recognition

The K. A. Johnson Lab – Nucleoside analogs and the mitochondrial DNA polymerase
Alternative nature – pokeweed, the source of the toxin pokeweed antiviral protein
Ricin – Structure and Mechanism
Access Excellence – monoclonal antibody production

Nitric Oxide and Viagra

The story of Viagra – discovery, etc.
Food and Drug Administration – Center for Drug Evaluation and Research viagra information

Prions

The Official Mad Cow Disease Home Page – Articles on Mad Cow disease, as well as other prion diseases
Scientific American – Stopping prions from going mad
Wikipedia article on prions

Resveratrol

The Sinclair Lab at Harvard Medical School – Research including the effects of resveratrol on aging
GrapeExpectations: The Resveratrol Story – from QuackWatch.org

Ribozymes

Biochemistry lectures on Ribozymes – Q+A descriptions and molecular structures ribozymes
University of Colorado Health Sciences Center –Ribozymes, gene therapy, HIV, cancer, catalytic RNA
Jack W. Szostak Department of Genetics Harvard Medical School –Current lab research directions

Shotgun Sequencing

Human Genome Project Information Site – Administered by the the U.S. Department of Energy
The National Human Genome Reseach Institute – Information on ethics and human genetics
Genome Center at the University of Washington
Genome Sequencing

Telomeres

Telomere and Telomerase Related Sites
Telomerase, Cellular Senescence and Cancer – Q+A and definitions to science terminology
Telomerase and telomere dynamics in cancer – Links and current applications for telomerase research
Life Extension Foundation – Telomerase: The 'Immortalizing' Enzyme: Update on Geron Corporation
Human Cloning Organization – Don't Be Duped by the Telomere Scare
Scientific American – Turning Back the Strands of Time

Thermo-Depolymerization

Changing World Technologies – the company that promises to bring TDP to the world
AnythingInto Oil – the Discovery Magazine article that brought attention to TDP

Visionaries of Science

X-ray Crystallography
The Pasteur Institute
Pasteur biography
DNA structure
James Watson
Rosalind Franklin